Antihistaminic action of pheniramine maleate is used to reduce symptoms related to allergy including sneezing, itching and watery eyes. A 22.7 mg single dose of pheniramine maleate reduced histamine induced skin reactions by >50% within minutes reflecting the rapid onset speed []. It blocks the H1 receptors and thus serves as a reliable remedy in allergic conditions, such as hay fever.
Pheniramine maleate has been found to be effective for 4-6 hours in a study and thus is used as acute medicine rather than daily use orally. While it may be less effective at treating specific allergies, you are also more likely to find this medication in combination with other ingredients that might treat a wider range of symptoms together compared to stand alone antihistamines. Examples include pheniramine maleate with decongestant such as pseudoephedrine to target nasal congestion and histaminic symptoms respectively.
One notes that pheniramine maleate is a powerful alternative, but you should also be aware of its sedative effects and potential impairment in cognitive and motor performance. Due to this trait, it is not suitable for those that want a vigilant state like when driving or using machines. Patients should also be warned about potential interactions with alcohol, seeing that both drugs have the capacity to increase drowsiness and affect coordination.
For adult dosage, one tablet of a strength 22.7 mg pheniramine maleate is usually taken every four to six hours provided that it shall not exceed a dose of greater than or equal to four times per day Higher doses lead to the side effects that we try and avoid – dry mouth, sedation & urinary retention. Hence by following the recommended dose you are assuring high efficiency and reducing side effects.
But to those who study pheniramine maleate uses, understanding it as an element in fast and non-drowsy relief from allergic reaction is a must. But its sedative nature and brief duration of action require careful use, the drug would also be unsuitable for instances where full cognitive function was necessary. You can visit Pheniramine Maleate uses for detailed information.